Analytical Ultracentrifugation

Technology / Methodology:
Interactions and characterization of biomolecules

CEITEC MU,  building A4, room 2.17

Research group:
CF: Core Facility Biomolecular Interaction and Crystallization


Beckman Coulter ProteomeLab XL-I analytical ultracentrifuge is equipped with absorbance (wavelength range 190 – 800 nm) and interference optics and can be used for both sedimentation velocity and sedimentation equilibrium experiments.

Analytical ultracentrifugation is applicable for proteins, nucleic acids, lipids, polysaccharides, viruses and nanoparticles. It has a broad applicability including determination of sample homogeneity, oligomeric state of proteins (or molecular weight, respectively) and can be used to assess aggregation of sample and to study biomolecular interactions of self- and hetero-association systems (determination of stoichiometry and affinity).

Analytical ultracentrifugation is in "service" mode - the instrument is operated by CF BIC staff.

Available services:

Sedimentation equilibrium

Sedimentation velocity

For more details, please contact responsible person:

Monika Kubíčková

phone: +420 549 49 25 27
​office : 3.39/A4