Differential scanning fluorimetry
Technology / Methodology:
Interactions and characterization of biomolecules
Location:
CEITEC MU, building C04, room 2.21
Research group:
CF: Core Facility Biomolecular Interaction and Crystallography
Prometheus precisely characterizes thermal unfolding, chemical denaturation and aggregation in a single run within broad temperature range (15 - 110 °C). It is possible to measure up to 48 samples in one run with very small volumes (20 µl per sample).
Possibility to measure not only unfolding of the sample but also re-folding with controlled decrease of temperature.
Backreflection optic allows to observe formulation of aggregation simultaneously with thermal unfolding.
The measurement at nanoDSF is supposed to be performed by users themselves after training.
For more details, please contact responsible person:
Eva Paulenová
e-mail: eva.paulenova@ceitec.muni.cz
phone: +420 549 49 78 22
office: 3.37/ C04
Josef Houser
e-mail: josef.houser@ceitec.cz
phone: +420 549 49 25 26
office : 3.39/C04
