Surface Plasmon Resonance

Technology / Methodology:
​Interactions and characterization of biomolecules

CEITEC MU,  building A4, room 2.18

Research group:
CF: Core Facility Biomolecular Interaction and Crystallization


Biacore T200 is a molecular interaction analysis system monitors real-time, label-free interaction ranging from ions to viruses. The system offers a powerful, versatile solution for obtaining the highest quality kinetic, affinity, concentration, specificity, selectivity, and thermodynamic data and can be used for multiple applications, from early research to drug discovery and development. In the arrangement, one of the interactants is immobilized on the
sensor chip surface, while the other is passed over that surface in solution. 
The increased sensitivity in Biacore T200 enables work on extremely low immobilization levels, returning cleaner data by avoiding artifacts from effects such as crowding, aggregation, or mass transport limitations. 

The system supports 96- and 384-well microplates, is it able to run up to 48 hours unattended operation and analyze up to 384 samples per run. Temperature control of sample compartment, analysis temperature range 4°C to 45°C. Integrated buffer degasser ensures data quality at elevated temperatures. Built-in buffer selector enables up to four different buffers to be tested at one time. Sample can be recovery for further identification.

Multichannel (36) SPR biosensor system for affinity studies of biomolecules, flow-through design, parallel analysis of samples. Universal gold layered chip for customized modification.

Measurement at BiacoreT200 or Multichannel SPR biosensor system is performed by users themselves.

For more details, please contact responsible person:

Josef Houser

phone: +420 549 49 25 26
​office : 3.39/A4